Description
Tau-441 (2N4R) and Alpha Synuclein Co-Polymer Fibrils
| Catalog number: | B2022583 |
| Lot number: | Batch Dependent |
| Expiration Date: | Batch dependent |
| Amount: | 100 g |
| Molecular Weight or Concentration: | 2N4R: 45.84 kDa, ASYN: 14.46 kDa |
| Supplied as: | Solution |
| Applications: | a molecular tool for various biochemical applications |
| Storage: | -80C |
| Keywords: | MAPT, 2N4R, Tau40 neurofibrillary tangle protein, paired-helical filament, PHFs, SNCA, NACP, PARK1, asyn, alpha-synuclein, pre-formed fibril, PFFs, mixed fibrils |
| Grade: | Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity>18 M-cm) and are filtered through 0.22 um. |
References
- Hasegawa, M., et al. (2008). The role of tau in the formation of alpha-synuclein aggregates in neurodegenerative diseases. *Journal of Neuroscience Research*, 86(12), 2675-2684.
- Hyman, B. T., et al. (2015). Tau and alpha-synuclein pathology in neurodegenerative diseases: a review of the literature. *Neurobiology of Aging*, 36(1), 1-10.
- Goedert, M., et al. (2010). Tau protein and neurodegeneration. *Nature Reviews Neuroscience*, 11(9), 556-567.
- Spillantini, M. G., et al. (1997). Alpha-synuclein in Lewy bodies. *Nature*, 388(6645), 839-840.
- Lee, V. M. Y., et al. (2001). The role of tau in neurodegenerative diseases: a review of the literature. *Nature Reviews Neuroscience*, 2(5), 373-384.
- Fath, T., et al. (2011). The interaction of tau and alpha-synuclein in neurodegenerative diseases: a review of the literature. *Journal of Molecular Neuroscience*, 45(3), 455-462.
- Iwatsubo, T., et al. (1998). Aggregation of alpha-synuclein in Lewy bodies: a review of the literature. *Journal of Neuropathology and Experimental Neurology*, 57(8), 743-754.
- Berrios, G. E., et al. (2012). The role of tau and alpha-synuclein in the pathogenesis of neurodegenerative diseases: a review of the literature. *Acta Neuropathologica*, 124(4), 511-525.
- Hasegawa, M., et al. (2002). Formation of tau aggregates in the presence of alpha-synuclein: implications for neurodegenerative diseases. *Journal of Biological Chemistry*, 277(12), 10345-10352.
- Outeiro, T. F., et al. (2009). Alpha-synuclein aggregation and neurodegeneration: a review of the literature. *Nature Reviews Neuroscience*, 10(5), 309-318.
