Description
DYRK2 Protein, Active
| Catalog number: | B2019370 |
| Lot number: | Batch Dependent |
| Expiration Date: | Batch dependent |
| Amount: | 5 g |
| Molecular Weight or Concentration: | 63.5 kDa |
| Supplied as: | Resin |
| Applications: | a molecular tool for various biochemical applications |
| Storage: | 70C |
| Keywords: | DYRK2 Protein, Active |
| Grade: | Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity>18 M-cm) and are filtered through 0.22 um. |
References
- Tandon V, de la Vega L, Banerjee S. Emerging roles of DYRK2 in cancer J Biol Chem. 2021 Jan-Jun;296:100233.
- Jimnez-Izquierdo R, Morrugares R, Suanes-Cobos L, Correa-Sez A, Garrido-Rodrguez M, Cerero-Tejero L, Khan OM, de la Luna S, Sancho R, Calzado MA. FBXW7 tumor suppressor regulation by dualspecificity tyrosine-regulated kinase 2 Cell Death Dis. 2023 Mar 18;14(3):202.
- Kamioka H, Yogosawa S, Oikawa T, Aizawa D, Ueda K, Saeki C, Haruki K, Shimoda M, Ikegami T, Nishikawa Y, Saruta M, Yoshida K. Dyrk2 gene transfer suppresses hepatocarcinogenesis by promoting the degradation of Myc and Hras JHEP Rep. 2023 Apr 6;5(7):100759.
- VerPlank JJS, Goldberg AL. Regulating protein breakdown through proteasome phosphorylation Biochem J. 2017 Sep 24;474(19):3355-3371.
- Lara-Chica M, Correa-Sez A, Jimnez-Izquierdo R, Garrido-Rodrguez M, Ponce FJ, Moreno R, Morrison K, Di Vona C, Arat K, Jimnez-Jimnez C, Morrugares R, Schmitz ML, de la Luna S, de la Vega L, Calzado MA. A novel CDC25A/DYRK2 regulatory switch modulates cell cycle and survival Cell Death Differ. 2022 Jan;29(1):105-117.
- Kawamura A, Yoshida S, Yoshida K. The diverse functions of DYRK2 in response to cellular stress Histol Histopathol. 2024 Nov;39(11):1427-1434.
- Moreno R, Banerjee S, Jackson AW, Quinn J, Baillie G, Dixon JE, Dinkova-Kostova AT, Edwards J, de la Vega L. The stress-responsive kinase DYRK2 activates heat shock factor 1 promoting resistance to proteotoxic stress Cell Death Differ. 2021 May;28(5):1563-1578.
- Yoshida S, Kawamura A, Aoki K, Wiriyasermkul P, Sugimoto S, Tomiyoshi J, Tajima A, Ishida Y, Katoh Y, Tsukada T, Tsuneoka Y, Yamada K, Nagamori S, Nakayama K, Yoshida K. Positive regulation of Hedgehog signaling via phosphorylation of GLI2/GLI3 by DYRK2 kinase Proc Natl Acad Sci U S A. 2024 Jul 9;121(28):e2320070121.
- Sun Y, Ge X, Li M, Xu L, Shen Y. Dyrk2 involved in regulating LPS-induced neuronal apoptosis Int J Biol Macromol. 2017 Nov;104(Pt A):979-986.









