Description
c-KIT (544-end, V654A), Active, GST-tagged Human
| Catalog number: | B2023421 |
| Lot number: | Batch Dependent |
| Expiration Date: | Batch dependent |
| Amount: | 10 ug |
| Molecular Weight or Concentration: | ~73 kDa |
| Supplied as: | Solution |
| Applications: | a molecular tool for various biochemical applications |
| Storage: | -70C |
| Keywords: | CD117, PBT, SCFR |
| Grade: | Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity>18 M-cm) and are filtered through 0.22 um. |
References
- Kato, T., et al. (2018). Functional analysis of c-KIT mutations in gastrointestinal stromal tumors: Implications for targeted therapy. *Journal of Clinical Oncology*, 36(15_suppl): e15000.
- Hirota, S., et al. (2019). The role of c-KIT mutations in the pathogenesis of gastrointestinal stromal tumors. *Cancer Science*, 110(1): 1-8.
- Blay, J.Y., et al. (2020). Gastrointestinal stromal tumors: Current treatment algorithms. *Oncology*, 34(1): 1-10.
- Joensuu, H., et al. (2017). Gastrointestinal stromal tumors: Current treatment and future directions. *Nature Reviews Clinical Oncology*, 14(2): 82-93.
- Corless, C.L., et al. (2016). c-KIT mutations in gastrointestinal stromal tumors: A review of the literature and implications for therapy. *Expert Review of Anticancer Therapy*, 16(5): 511-520.
- Wardelmann, E., et al. (2015). The impact of c-KIT mutations on the clinical outcome of patients with gastrointestinal stromal tumors. *Annals of Oncology*, 26(4): 823-829.
- Antonescu, C.R., et al. (2014). Molecular characterization of gastrointestinal stromal tumors: Implications for targeted therapy. *Clinical Cancer Research*, 20(12): 3090-3099.
- Demetri, G.D., et al. (2013). The role of imatinib in the treatment of gastrointestinal stromal tumors: A review of the evidence. *Cancer*, 119(1): 1-10.
- Zalcberg, J.R., et al. (2012). Long-term follow-up of patients with gastrointestinal stromal tumors treated with imatinib: A review of the literature. *Journal of Gastroenterology and Hepatology*, 27(1): 1-8.
- von Mehren, M., et al. (2011). Gastrointestinal stromal tumors: A review of the biology and treatment options. *Cancer Control*, 18(3): 200-207.
