Description
Phospho-Stat6 (Tyr641) Antibody APC Conjugate
| Catalog number: | B2018576 |
| Lot number: | Batch Dependent |
| Expiration Date: | Batch dependent |
| Amount: | 10 ug |
| Molecular Weight or Concentration: | 94.14 kDa |
| Supplied as: | Solution |
| Applications: | a molecular tool for various biochemical applications |
| Storage: | 2-8 |
| Keywords: | Signal transducer and activator of transcription 6, IL-4 Stat |
| Grade: | Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity>18 M-cm) and are filtered through 0.22 um. |
References
- Xue Y, Gao S, Gou J, Yin T, He H, Wang Y, Zhang Y, Tang X, Wu R. Platinum-based chemotherapy in combination with PD-1/PD-L1 inhibitors: preclinical and clinical studies and mechanism of action Expert Opin Drug Deliv. 2021 Feb;18(2):187-203.
- Lin Y, Li B, Yang X, Liu T, Shi T, Deng B, Zhang Y, Jia L, Jiang Z, He R. Non-hematopoietic STAT6 induces epithelial tight junction dysfunction and promotes intestinal inflammation and tumorigenesis Mucosal Immunol. 2019 Nov;12(6):1304-1315.
- Hupfer T, Schick J, Jozefowski K, Voehringer D, Ostrop J, Lang R. Stat6-Dependent Inhibition of Mincle Expression in Mouse and Human Antigen-Presenting Cells by the Th2 Cytokine IL-4 Front Immunol. 2016 Oct 14;7:423.
- Usui T. Transcription factors that regulate helper T cell differentiation Nihon Rinsho Meneki Gakkai Kaishi. 2007 Dec;30(6):419-27.
- Heath VL, Murphy EE, Crain C, Tomlinson MG, OGarra A. TGF-beta1 down-regulates Th2 development and results in decreased IL-4-induced STAT6 activation and GATA-3 expression Eur J Immunol. 2000 Sep;30(9):2639-49.
- Amsen D, Blander JM, Lee GR, Tanigaki K, Honjo T, Flavell RA. Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells Cell. 2004 May 14;117(4):515-26.
- Amo L, Dez-Garca J, Tamayo-Orbegozo E, Maruri N, Larrucea S. Podocalyxin Expressed in Antigen Presenting Cells Promotes Interaction With T Cells and Alters Centrosome Translocation to the Contact Site Front Immunol. 2022 May 31;13:835527.
- Su CW, Chen CY, Jiao L, Long SR, Mao T, Ji Q, ODonnell S, Stanton C, Zheng S, Walker WA, Cherayil BJ, Shi HN. Helminth-Induced and Th2-Dependent Alterations of the Gut Microbiota Attenuate Obesity Caused by High-Fat Diet Cell Mol Gastroenterol Hepatol. 2020;10(4):763-778.
- Yuda H, Adachi Y, Taguchi O, Gabazza EC, Hataji O, Fujimoto H, Tamaki S, Nishikubo K, Fukudome K, DAlessandro-Gabazza CN, Maruyama J, Izumizaki M, Iwase M, Homma I, Inoue R, Kamada H, Hayashi T, Kasper M, Lambrecht BN, Barnes PJ, Suzuki K. Activated protein C inhibits bronchial hyperresponsiveness and Th2 cytokine expression in mice Blood. 2004 Mar 15;103(6):2196-204.









