Sale!
Cancer Antigen 72-4 (CA 72-4)

Cancer Antigen 72-4 (CA 72-4)

Original price was: $150.00.Current price is: $37.50.

SKU: PW14836850627 Category:

Description

Cancer Antigen 72-4 (CA 72-4) Catalog number: B2012168 (1 kU)

Catalog number: B2012168
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 kU
Molecular Weight or Concentration: > 100 kU/mL
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -20C
Keywords: CA 72-4, Cancer Antigen 72-4, Cancer Antigen Tag-72
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity>18 M-cm) and are filtered through 0.22 um.

Cancer Antigen 72-4 (CA 72-4) is provided as a biotechnology-grade solution in a defined 1kU fill (Catalog B2012168) with a listed concentration of > 100kU/mL. The supplier describes this product as purified from human metastatic liver carcinoma and positions it as a molecular tool for various biochemical applications. Storage is specified at 20C. The clear documentation fieldsamount, concentration, supplied-as, storage, and keyword synonymsfacilitate SOP inclusion and inventory control for labs standardizing antigen-related workflows.

In method development, a well-characterized CA72-4 preparation supports exploratory immunochemical work such as assembling capture/detection elements, mapping buffer and wash conditions, and running qualitative readouts to benchmark signal windows and background. Because this listing is a research reagent rather than a prequalified diagnostic component, it is good practice to establish working dilutions empirically in small pilots, document buffer composition and time-at-temperature, and record lot identifiers to enable reproducibility across runs and analysts. The biotechnology-grade note (solutions prepared with TypeI ultrapure water and filtered through 0.22um) aligns with expectations for low background during optimization.

Typical research uses include preparing internal references for comparative experiments, evaluating sample-preparation variables that influence antigen presentation, and training or platform-qualification runs that require a defined antigen source. The ready-to-use solution format minimizes reconstitution variability and simplifies titration across assay formats. Within these research-only boundaries, CA72-4 in this presentation functions as a dependable, precisely specified component for teams standardizing immunochemical and biochemical workflows.

Why researchers choose this product:

  • Defined 1kU fill with listed concentration > 100kU/mL for clear documentation
  • Ready-to-use solution format supports rapid pilot titrations and method setup
  • Specified storage at 20C for routine cold-chain handling
  • Biotechnology-grade preparation (Type I water; 0.22um filtration for solutions)
  • Keyword synonyms (CA72-4, Cancer Antigen 72-4, Cancer Antigen Tag-72) aid searchability and SOP alignment

This product is for Research Use Only (RUO). It is not intended for diagnostic or therapeutic use.

References

  • 1: Reck M, Rodrguez-Abreu D, Robinson AG, Hui R, Csszi T, Flp A, Gottfried M, Peled N, Tafreshi A, Cuffe S, OBrien M, Rao S, Hotta K, Leiby MA, Lubiniecki GM, Shentu Y, Rangwala R, Brahmer JR; KEYNOTE-024 Investigators. Pembrolizumab versus Chemotherapy for PD-L1-Positive Non-Small-Cell Lung Cancer N Engl J Med. 2016 Nov 10;375(19):1823-1833.
  • 2: Xu Y, Zhang P, Zhang K, Huang C. The application of CA72-4 in the diagnosis, prognosis, and treatment of gastric cancer Biochim Biophys Acta Rev Cancer. 2021 Dec;1876(2):188634.
  • 3: Gao Y, Wang J, Zhou Y, Sheng S, Qian SY, Huo X. Evaluation of Serum CEA, CA19-9, CA72-4, CA125 and Ferritin as Diagnostic Markers and Factors of Clinical Parameters for Colorectal Cancer Sci Rep. 2018 Feb 9;8(1):2732.
  • 4: Mariampillai AI, Cruz JPD, Suh J, Sivapiragasam A, Nevins K, Hindenburg AA. Cancer Antigen 72-4 for the Monitoring of Advanced Tumors of the Gastrointestinal Tract, Lung, Breast and Ovaries Anticancer Res. 2017 Jul;37(7):3649-3656.
  • 5: Li M, Men X, Zhang X. Diagnostic value of carbohydrate antigen 72-4 combined with carbohydrate antigen 15.3 in ovarian cancer, cervical cancer and endometrial cancer J BUON. 2020 Jul-Aug;25(4):1918-1927.
  • 6: Virgilio E, Proietti A, DUrso R, Cardelli P, Giarnieri E, Giovagnoli MR, Montagnini M, Villani S, Balducci G, Cavallini M. Elevated Gastric Juice Carbohydrate Antigen 72.4 (Ca 72.4) Is an Independent Prognostic Factor of Poor Survival for Gastric Cancer Patients Anticancer Res. 2020 Mar;40(3):1691-1695.
  • 7: Duan T, Chen X, Wu J, Li R, Guo H, Du J, Guo J. Serum carbohydrate antigen 72-4 concentrations decrease with age in females but not in males in Beijing, China Ann Clin Biochem. 2021 Nov;58(6):556-562.
  • 8: Shimada H, Noie T, Ohashi M, Oba K, Takahashi Y. Clinical significance of serum tumor markers for gastric cancer: a systematic review of literature by the Task Force of the Japanese Gastric Cancer Association Gastric Cancer. 2014 Jan;17(1):26-33.
  • 9: Huang L, Xu A, Li T, Han W, Wu S, Wang Y. Detection of perioperative cancer antigen 72-4 in gastric juice pre- and post-distal gastrectomy and its significances Med Oncol. 2013;30(3):651.
  • 10: Buderath P, Kasimir-Bauer S, Aktas B, Rasch J, Kimmig R, Zeller T, Heubner M. Evaluation of a novel ELISA for the tumor-associated antigen CA 72-4 in patients with ovarian cancer Future Sci OA. 2016 Oct 12;2(4):FSO145. pubmed.ncbi.nlm.nih.gov

Related products