Description
Human FGF-8b (Fibroblast Growth Factor-8b)
| Catalog number: | B2018710 |
| Lot number: | Batch Dependent |
| Expiration Date: | Batch dependent |
| Amount: | 1 ug |
| Molecular Weight or Concentration: | ~21 kDa |
| Supplied as: | Powder |
| Applications: | a molecular tool for various biochemical applications |
| Storage: | -20C |
| Keywords: | FGF-8b, Fibroblast Growth Factor 8b |
| Grade: | Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity>18 M-cm) and are filtered through 0.22 um. |
References
- Ruohola JK, Viitanen TP, Valve EM, Seppnen JA, Loponen NT, Keskitalo JJ, Lakkakorpi PT, Hrknen PL. Enhanced invasion and tumor growth of fibroblast growth factor 8b-overexpressing MCF-7 human breast cancer cells Cancer Res. 2001 May 15;61(10):4229-37.
- Nilsson EM, Brokken LJ, Narvi E, Kallio MJ, Hrknen PL. Identification of fibroblast growth factor-8b target genes associated with early and late cell cycle events in breast cancer cells Mol Cell Endocrinol. 2012 Jul 6;358(1):104-15.
- Mark RJ, Fuson KS, Keane-Lazar K, May PC. Fibroblast growth factor-8 protects cultured rat hippocampal neurons from oxidative insult Brain Res. 1999 May 29;830(1):88-93.
- Valta MP, Tuomela J, Vuorikoski H, Loponen N, Vnnen RM, Pettersson K, Vnnen HK, Hrknen PL. FGF-8b induces growth and rich vascularization in an orthotopic PC-3 model of prostate cancer J Cell Biochem. 2009 Jul 1;107(4):769-84.
- Elo TD, Valve EM, Seppnen JA, Vuorikoski HJ, Mkel SI, Poutanen M, Kujala PM, Hrknen PL. Stromal activation associated with development of prostate cancer in prostate-targeted fibroblast growth factor 8b transgenic mice Neoplasia. 2010 Nov;12(11):915-27.
- Valta MP, Hentunen T, Qu Q, Valve EM, Harjula A, Seppnen JA, Vnnen HK, Hrknen PL. Regulation of osteoblast differentiation: a novel function for fibroblast growth factor 8 Endocrinology. 2006 May;147(5):2171-82.
- Nilsson EM, Brokken LJ, Hrknen PL. Fibroblast growth factor 8 increases breast cancer cell growth by promoting cell cycle progression and by protecting against cell death Exp Cell Res. 2010 Mar 10;316(5):800-12.
- Tanaka A, Furuya A, Yamasaki M, Hanai N, Kuriki K, Kamiakito T, Kobayashi Y, Yoshida H, Koike M, Fukayama M. High frequency of fibroblast growth factor (FGF) 8 expression in clinical prostate cancers and breast tissues, immunohistochemically demonstrated by a newly established neutralizing monoclonal antibody against FGF 8 Cancer Res. 1998 May 15;58(10):2053-6.
- Lin X, Song L, He D, Zeng X, Wu J, Luo W, Yang Q, Wang J, Wang T, Cai J, Lin Y, Lai F, Peng W, Wu X. An FGF8b-mimicking peptide with potent antiangiogenic activity Mol Med Rep. 2017 Jul;16(1):894-900.
