Description
Human AKR7A2 Protein (Highly Pure)
| Catalog number: | B2011568 |
| Lot number: | Batch Dependent |
| Expiration Date: | Batch dependent |
| Amount: | 100 g |
| Molecular Weight or Concentration: | 0.5 mg/mL |
| Supplied as: | Solution |
| Applications: | molecular tool for various biochemical applications |
| Storage: | -20 C |
| Keywords: | AKR7A2 protein (His tag), Purified recombinant Human AKR7A2 protein, AKRA2 7 protein, AFB1AR1 protein, aldoketoreductase 7., aflatoxin aldehyde reductase protein, aflatoxin beta1 aldehyde reductase protein, AFAR1 protein, AKR7 protein, member A2 AFB1 AR1 protein, member A2 protein, AKR7A2, aldo keto reductase family 7 protein, AKRA2 7, aldo keto reductase family 7 protein, aldo-keto reductase family 7 protein, AFAR protein, AKRA2-7, Aflatoxin B1 aldehyde reductase member 2 protein, Aiar protein, AFB1-AR1 protein, AKRA2-7 protein |
| Grade: | Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity>18 M-cm) and are filtered through 0.22 um. |
References
- Quiones-Lombraa A, Intini A, Blanco JG. Insights into the transcriptional regulation of the anthracycline reductase AKR7A2 in human cardiomyocytes Toxicol Lett. 2019 Jun 1;307:11-16.
- Hoefer CC, Quiones-Lombraa A, Blair RH, Blanco JG. Role of DNA Methylation on the Expression of the Anthracycline Metabolizing Enzyme AKR7A2 in Human Heart Cardiovasc Toxicol. 2016 Apr;16(2):182-92.
- Li X, Zou S, Li Z, Cai G, Chen B, Wang P, Dong W. The identification of human aldo-keto reductase AKR7A2 as a novel cytoglobin-binding partner Cell Mol Biol Lett. 2016 Oct 24;21:25.
- Li D, Ferrari M, Ellis EM. Human aldo-keto reductase AKR7A2 protects against the cytotoxicity and mutagenicity of reactive aldehydes and lowers intracellular reactive oxygen species in hamster V79-4 cells Chem Biol Interact. 2012 Jan 5;195(1):25-34.
- Bahari A, Mehrzad J, Mahmoudi M, Bassami MR, Dehghani H. GST-M1 is transcribed moreso than AKR7A2 in AFB-exposed human monocytes and lymphocytes J Immunotoxicol. 2015 Apr-Jun;12(2):194-8.
- Li D, Ma S, Ellis EM. Nrf2-mediated adaptive response to methyl glyoxal in HepG2 cells involves the induction of AKR7A2 Chem Biol Interact. 2015 Jun 5;234:366-71.
- Quiones-Lombraa A, Ferguson D, Hageman Blair R, Kalabus JL, Redzematovic A, Blanco JG. Interindividual variability in the cardiac expression of anthracycline reductases in donors with and without Down syndrome Pharm Res. 2014 Jul;31(7):1644-55.
- Picklo MJ Sr, Olson SJ, Hayes JD, Markesbery WR, Montine TJ. Elevation of AKR7A2 (succinic semialdehyde reductase) in neurodegenerative disease Brain Res. 2001 Oct 19;916(1-2):229-38.
- Oconnor T, Ireland LS, Harrison DJ, Hayes JD. Major differences exist in the function and tissue-specific expression of human aflatoxin B1 aldehyde reductase and the principal human aldo-keto reductase AKR1 family members Biochem J. 1999 Oct 15;343 Pt 2(Pt 2):487-504.
