Description
Ebelactone A
| Catalog number: | MDP0534 |
| CAS Number: | 136132-68-8 |
| Sequence: | 3,11-Dihydroxy-2,4,6,8,10,12-hexamethyl-9-oxo-(E)-6-tetradecen-3-olide |
| Amount: | 5 mg |
| Molecular Weight: | 338.4 g/mol |
| Supplied as: | Powder |
| Applications: | molecular tool for various biochemical applications |
| Storage: | -20 C |
| WARNING: | For in vitro Research Use Only. NOT for use on humans or animals. |
| Grade: | Biotechnology grade. All products are highly pure. |
References
- Wyatt MA, Ahilan Y, Argyropoulos P, Boddy CN, Magarvey NA, Harrison PH. Biosynthesis of ebelactone A: isotopic tracer, advanced precursor and genetic studies reveal a thioesterase-independent cyclization to give a polyketide -lactone J Antibiot (Tokyo). 2013 Jul;66(7):421-30.
- Nonaka Y, Ohtaki H, Ohtsuka E, Kocha T, Fukuda T, Takeuchi T, Aoyagi T. Effects of ebelactone B, a lipase inhibitor, on intestinal fat absorption in the rat J Enzyme Inhib. 1996;10(1):57-63.
- Uotani K, Naganawa H, Aoyagi T, Umezawa H. Biosynthetic studies of ebelactone A and B by 13C NMR spectrometry J Antibiot (Tokyo). 1982 Dec;35(12):1670-4.
- Archibald SC, Barden DJ, Bazin JF, Fleming I, Foster CF, Mandal AK, Mandal AK, Parker D, Takaki K, Ware AC, Williams AR, Zwicky AB. Stereocontrol in organic synthesis using silicon-containing compounds. Studies directed towards the synthesis of ebelactone A Org Biomol Chem. 2004 Apr 7;2(7):1051-64.
- Uotani K, Naganawa H, Kondo S, Aoyagi T, Umezawa H. Structural studies on ebelactone A and B, esterase inhibitors produced by actinomycetes J Antibiot (Tokyo). 1982 Nov;35(11):1495-9.
- Mandal AK. Stereocontrolled total synthesis of (-)-ebelactone A Org Lett. 2002 Jun 13;4(12):2043-5.
- De Pascale G, Nazi I, Harrison PH, Wright GD. -Lactone natural products and derivatives inactivate homoserine transacetylase, a target for antimicrobial agents J Antibiot (Tokyo). 2011 Jul;64(7):483-7.
- Burnette TC, Harrington JA, Reardon JE, Merrill BM, de Miranda P. Purification and characterization of a rat liver enzyme that hydrolyzes valaciclovir, the L-valyl ester prodrug of acyclovir J Biol Chem. 1995 Jun 30;270(26):15827-31.
- Umezawa H, Aoyagi T, Uotani K, Hamada M, Takeuchi T, Takahashi S. Ebelactone, an inhibitor of esterase, produced by actinomycetes J Antibiot (Tokyo). 1980 Dec;33(12):1594-6.
