Description
Human Raf-1 Protein Kinase
| Catalog number: | B2013329 |
| Lot number: | Batch Dependent |
| Expiration Date: | Batch dependent |
| Amount: | 1 ug |
| Molecular Weight or Concentration: | 74 kDa |
| Supplied as: | Solution |
| Applications: | molecular tool for various biochemical applications |
| Storage: | -20C |
| Keywords: | Raf-1 Protein Kinase human |
| Grade: | Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity>18 M-cm) and are filtered through 0.22 um. |
References
- Odabaei G, Chatterjee D, Jazirehi AR, Goodglick L, Yeung K, Bonavida B. Raf-1 kinase inhibitor protein: structure, function, regulation of cell signaling, and pivotal role in apoptosis Adv Cancer Res. 2004;91:169-200.
- Mas VM, Hernandez H, Plo I, Bezombes C, Maestre N, Quillet-Mary A, Filomenko R, Demur C, Jaffrzou JP, Laurent G. Protein kinase Czeta mediated Raf-1/extracellular-regulated kinase activation by daunorubicin Blood. 2003 Feb 15;101(4):1543-50.
- Hindley A, Kolch W. Raf-1 and B-Raf promote protein kinase C theta interaction with BAD Cell Signal. 2007 Mar;19(3):547-55.
- Magnuson NS, Beck T, Vahidi H, Hahn H, Smola U, Rapp UR. The Raf-1 serine/threonine protein kinase Semin Cancer Biol. 1994 Aug;5(4):247-53.
- King AJ, Sun H, Diaz B, Barnard D, Miao W, Bagrodia S, Marshall MS. The protein kinase Pak3 positively regulates Raf-1 activity through phosphorylation of serine 338 Nature. 1998 Nov 12;396(6707):180-3.
- Illario M, Cavallo AL, Bayer KU, Di Matola T, Fenzi G, Rossi G, Vitale M. Calcium/calmodulin-dependent protein kinase II binds to Raf-1 and modulates integrin-stimulated ERK activation J Biol Chem. 2003 Nov 14;278(46):45101-8.
- Hambleton J, McMahon M, DeFranco AL. Activation of Raf-1 and mitogen-activated protein kinase in murine macrophages partially mimics lipopolysaccharide-induced signaling events J Exp Med. 1995 Jul 1;182(1):147-54.
- Kharbanda S, Saleem A, Emoto Y, Stone R, Rapp U, Kufe D. Activation of Raf-1 and mitogen-activated protein kinases during monocytic differentiation of human myeloid leukemia cells J Biol Chem. 1994 Jan 14;269(2):872-8.
- Lee M, Koh WS, Han SS. Down-regulation of Raf-1 kinase is associated with paclitaxel resistance in human breast cancer MCF-7/Adr cells Cancer Lett. 2003 Apr 10;193(1):57-64.
