Description
Phospho-Stat1 (Tyr701) Rabbit PE Conjugate
| Catalog number: | B2018881 |
| Lot number: | Batch Dependent |
| Expiration Date: | Batch dependent |
| Amount: | 10 ug |
| Molecular Weight or Concentration: | 87.34 kDa |
| Supplied as: | Solution |
| Applications: | a molecular tool for various biochemical applications |
| Storage: | 2-8 |
| Keywords: | Signal transducer and activator of transcription 1-alpha/beta, Transcription factor ISGF-3 components p91/p84 |
| Grade: | Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity>18 M-cm) and are filtered through 0.22 um. |
References
- Nakayama Y, Mimura K, Tamaki T, Shiraishi K, Kua LF, Koh V, Ohmori M, Kimura A, Inoue S, Okayama H, Suzuki Y, Nakazawa T, Ichikawa D, Kono K. PhosphoSTAT1 expression as a potential biomarker for antiPD1/antiPDL1 immunotherapy for breast cancer Int J Oncol. 2019 Jun;54(6):2030-2038.
- Menon PR, Staab J, Gregus A, Wirths O, Meyer T. An inhibitory effect on the nuclear accumulation of phospho-STAT1 by its unphosphorylated form Cell Commun Signal. 2022 Mar 31;20(1):42.
- Beckman JD, DaSilva A, Aronovich E, Nguyen A, Nguyen J, Hargis G, Reynolds D, Vercellotti GM, Betts B, Wood DK. JAK-STAT inhibition reduces endothelial prothrombotic activation and leukocyte-endothelial proadhesive interactions J Thromb Haemost. 2023 May;21(5):1366-1380.
- Bernasconi AR, Yancoski J, Villa M, Oleastro MM, Galicchio M, Rossi JG. Increased STAT1 Amounts Correlate with the Phospho-STAT1 Level in STAT1 Gain-of-function Defects J Clin Immunol. 2018 Oct;38(7):745-747.
- Metwally H, Elbrashy MM, Ozawa T, Okuyama K, White JT, Tulyeu J, Sndergaard JN, Wing JB, Muratsu A, Matsumoto H, Ikawa M, Kishi H, Taniuchi I, Kishimoto T. Threonine phosphorylation of STAT1 restricts interferon signaling and promotes innate inflammatory responses Proc Natl Acad Sci U S A. 2024 Apr 23;121(17):e2402226121.
- Solimando AG, Desantis V, Palumbo C, Marasco C, Pappagallo F, Montagnani M, Ingravallo G, Cicco S, Di Paola R, Tabares P, Beilhack A, Dammacco F, Ria R, Vacca A. STAT1 overexpression triggers aplastic anemia: a pilot study unravelling novel pathogenetic insights in bone marrow failure Clin Exp Med. 2023 Oct;23(6):2687-2694.
- Huang R, Faratian D, Sims AH, Wilson D, Thomas JS, Harrison DJ, Langdon SP. Increased STAT1 signaling in endocrine-resistant breast cancer PLoS One. 2014 Apr 11;9(4):e94226.
- Scott O, Lindsay K, Erwood S, Mollica A, Roifman CM, Cohn RD, Ivakine EA. STAT1 gain-of-function heterozygous cell models reveal diverse interferon-signature gene transcriptional responses NPJ Genom Med. 2021 May 14;6(1):34.
- Hong S, Song MR. STAT3 but not STAT1 is required for astrocyte differentiation PLoS One. 2014 Jan 23;9(1):e86851.
