Description
Plasmepsin V FRET Substrate
| Catalog number: | B2011254 |
| Lot number: | Batch Dependent |
| Expiration Date: | Batch dependent |
| Amount: | 1 mg |
| Molecular Weight or Concentration: | 1751.1 g/mol |
| Supplied as: | Lyophilized |
| Applications: | molecular tool for various biochemical applications |
| Storage: | -20 C |
| Keywords: | PMV substrate |
| Grade: | Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity>18 M-cm) and are filtered through 0.22 um. |
References
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- Brancucci NMB, Heussler VT, Grring C. Targeting Plasmodium Plasmepsin V: Hitting Two Birds with One Stone Trends Parasitol. 2020 Feb;36(2):85-87.
- Barber J, Sikakana P, Sadler C, Baud D, Valentin JP, Roberts R. A target safety assessment of the potential toxicological risks of targeting plasmepsin IX/X for the treatment of malaria Toxicol Res (Camb). 2021 Feb 15;10(2):203-213.
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- Kinena L, Leitis G, Kanepe-Lapsa I, Bobrovs R, Jaudzems K, Ozola V, Suna E, Jirgensons A. Azole-based non-peptidomimetic plasmepsin inhibitors Arch Pharm (Weinheim). 2018 Sep;351(9):e1800151.
- Cheuka PM, Dziwornu G, Okombo J, Chibale K. Plasmepsin Inhibitors in Antimalarial Drug Discovery: Medicinal Chemistry and Target Validation (2000 to Present) J Med Chem. 2020 May 14;63(9):4445-4467.
- Zogota R, Kinena L, Withers-Martinez C, Blackman MJ, Bobrovs R, Pantelejevs T, Kanepe-Lapsa I, Ozola V, Jaudzems K, Suna E, Jirgensons A. Peptidomimetic plasmepsin inhibitors with potent anti-malarial activity and selectivity against cathepsin D Eur J Med Chem. 2019 Feb 1;163:344-352.
- Meissner KA, Kronenberger T, Maltarollo VG, Trossini GHG, Wrenger C. Targeting the Plasmodium falciparum plasmepsin V by ligand-based virtual screening Chem Biol Drug Des. 2019 Mar;93(3):300-312.
