Description
Recombinant HIPK3 (163-562) Protein
| Catalog number: | B2017499 |
| Lot number: | Batch Dependent |
| Expiration Date: | Batch dependent |
| Amount: | 20 g |
| Molecular Weight or Concentration: | 46.6 kDa |
| Supplied as: | Solution |
| Applications: | a molecular tool for various biochemical applications |
| Storage: | -80C |
| Keywords: | Homeodomain Interacting Protein Kinase 3, DYRK6, FIST3, YAK1 |
| Grade: | Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity>18 M-cm) and are filtered through 0.22 um. |
References
- Wang J, Zhao SY, Ouyang SS, Huang ZK, Luo Q, Liao L. [Circular RNA circHIPK3 acts as the sponge of microRNA-124 to promote human oral squamous cell carcinoma cells proliferation] Zhonghua Kou Qiang Yi Xue Za Zhi. 2018 Aug 9;53(8):546-551.
- Jnne OA, Moilanen AM, Poukka H, Rouleau N, Karvonen U, Kotaja N, Hkli M, Palvimo JJ. Androgen-receptor-interacting nuclear proteins Biochem Soc Trans. 2000;28(4):401-5.
- Han C, Wang S, Wang H, Zhang J. Exosomal circ-HIPK3 Facilitates Tumor Progression and Temozolomide Resistance by Regulating miR-421/ZIC5 Axis in Glioma Cancer Biother Radiopharm. 2021 Sep;36(7):537-548.
- Rochat-Steiner V, Becker K, Micheau O, Schneider P, Burns K, Tschopp J. FIST/HIPK3: a Fas/FADD-interacting serine/threonine kinase that induces FADD phosphorylation and inhibits fas-mediated Jun NH(2)-terminal kinase activation J Exp Med. 2000 Oct 16;192(8):1165-74.
- Schmitz M, Kaltheuner IH, Anand K, Dster R, Moecking J, Monastyrskyi A, Duckett DR, Roush WR, Geyer M. The reversible inhibitor SR-4835 binds Cdk12/cyclin K in a noncanonical G-loop conformation J Biol Chem. 2024 Jan;300(1):105501.
- Kaltheuner IH, Anand K, Moecking J, Dster R, Wang J, Gray NS, Geyer M. Abemaciclib is a potent inhibitor of DYRK1A and HIP kinases involved in transcriptional regulation Nat Commun. 2021 Nov 16;12(1):6607.
- Sierra OL, Towler DA. Runx2 trans-activation mediated by the MSX2-interacting nuclear target requires homeodomain interacting protein kinase-3 Mol Endocrinol. 2010 Jul;24(7):1478-97.
- Kim YH, Choi CY, Lee SJ, Conti MA, Kim Y. Homeodomain-interacting protein kinases, a novel family of co-repressors for homeodomain transcription factors J Biol Chem. 1998 Oct 2;273(40):25875-9.
- Wang Y, Zhao R, Shen C, Liu W, Yuan J, Li C, Deng W, Wang Z, Zhang W, Ge J, Shi B. Exosomal CircHIPK3 Released from Hypoxia-Induced Cardiomyocytes Regulates Cardiac Angiogenesis after Myocardial Infarction Oxid Med Cell Longev. 2020 Jul 13;2020:8418407.
