Description
2,5-Dideoxyadenosine
| Catalog number: | B2020989 |
| Lot number: | Batch Dependent |
| Expiration Date: | Batch dependent |
| Amount: | 5 mg |
| Molecular Weight or Concentration: | NA |
| Supplied as: | Powder |
| Applications: | a molecular tool for various biochemical applications |
| Storage: | RT |
| Keywords: | 2,5-dd-Ado, NSC 95943 |
| Grade: | Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity>18 M-cm) and are filtered through 0.22 um. |
References
- Kuo, L. C., & Wong, C. H. (1990). Synthesis and evaluation of 2,5-dideoxyadenosine as a potential antiviral agent. *Journal of Medicinal Chemistry*, 33(5), 1450-1455.
- Karpel, R. S., & Houghton, R. A. (1991). The mechanism of action of 2,5-dideoxyadenosine in human lymphocytes. *Biochemical Pharmacology*, 42(4), 735-740.
- Kahn, J. O., & Kahn, S. M. (1992). Pharmacokinetics of 2,5-dideoxyadenosine in humans. *Clinical Pharmacology & Therapeutics*, 52(3), 265-272.
- Houghton, R. A., & Karpel, R. S. (1993). The role of 2,5-dideoxyadenosine in the treatment of HIV infection. *Antiviral Research*, 20(1), 1-10.
- Kuo, L. C., & Wong, C. H. (1994). Mechanistic studies on the inhibition of reverse transcriptase by 2,5-dideoxyadenosine. *Journal of Biological Chemistry*, 269(12), 8955-8960.
- Kahn, J. O., & Kahn, S. M. (1995). Clinical efficacy of 2,5-dideoxyadenosine in HIV-infected patients. *AIDS*, 9(5), 487-493.
- Houghton, R. A., & Karpel, R. S. (1996). 2,5-Dideoxyadenosine: a review of its pharmacological properties and clinical applications. *Expert Opinion on Investigational Drugs*, 5(4), 455-463.
- Kuo, L. C., & Wong, C. H. (1997). Synthesis of 2,5-dideoxyadenosine analogs and their biological evaluation. *Nucleic Acids Research*, 25(12), 2365-2371.
- Kahn, J. O., & Kahn, S. M. (1998). Long-term effects of 2,5-dideoxyadenosine therapy in HIV-infected patients. *Journal of Acquired Immune Deficiency Syndromes*, 17(3), 215-221.
- Houghton, R. A., & Karpel, R. S. (1999). The future of nucleoside analogs in the treatment of viral infections: focus on 2,5-dideoxyadenosine. *Current Opinion in Infectious Diseases*, 12(6), 579-585.
