Description
Big Endothelin-3 (Rat, 1-41 Amide)
| Catalog number: | MDP0642 |
| CAS Number: | N/A |
| Sequence: | Cys-Thr-Cys-Phe-Thr-Tyr-Lys-Asp-Lys-Glu-Cys-Val-Tyr-Tyr-Cys-His-Leu-Asp-Ile-Ile-Trp-Ile-Asn-Thr-Pro-Glu-Gln-Thr-Val-Pro-Tyr-Gly-Leu-Ser-Asn-His-Arg-Gly-Ser-Leu-Arg-NH2 (Disulfide bonds between Cys1-Cys15 and Cys3-Cys11) |
| Amount: | 100 ug |
| Molecular Weight: | 4863.2 g/mol |
| Supplied as: | Powder |
| Applications: | molecular tool for various biochemical applications |
| Storage: | -20 C |
| WARNING: | For in vitro Research Use Only. NOT for use on humans or animals. |
| Grade: | Biotechnology grade. All products are highly pure. |
References
- Wallace JL, Keenan CM, MacNaughton WK, McKnight GW. Comparison of the effects of endothelin-1 and endothelin-3 on the rat stomach Eur J Pharmacol. 1989 Aug 11;167(1):41-7.
- Skovsted GF, Kilic S, Edvinsson L. Endothelin-1 and Endothelin-3 Regulate Endothelin Receptor Expression in Rat Coronary Arteries Basic Clin Pharmacol Toxicol. 2015 Nov;117(5):297-305.
- Sluck JM, Lin RC, Katolik LI, Jeng AY, Lehmann JC. Endothelin converting enzyme-1-, endothelin-1-, and endothelin-3-like immunoreactivity in the rat brain Neuroscience. 1999;91(4):1483-97.
- Matsumura Y, Fujita K, Takaoka M, Morimoto S. Big endothelin-3-induced hypertension and its inhibition by phosphoramidon in anaesthetized rats Eur J Pharmacol. 1993 Jan 5;230(1):89-93.
- Trybulec M, Dudek RR, Gryglewski RJ. Effects of endothelin-1 and endothelin-3 on the release of prostanoids from isolated perfused rat kidney J Cardiovasc Pharmacol. 1991;17 Suppl 7:S229-32.
- Matsumoto H, Suzuki N, Onda H, Fujino M. Abundance of endothelin-3 in rat intestine, pituitary gland and brain Biochem Biophys Res Commun. 1989 Oct 16;164(1):74-80.
- Henshall DC, Butcher SP, Sharkey J. A rat model of endothelin-3-induced middle cerebral artery occlusion with controlled reperfusion Brain Res. 1999 Oct 2;843(1-2):105-11.
- Warner TD, Mitchell JA, de Nucci G, Vane JR. Endothelin-1 and endothelin-3 release EDRF from isolated perfused arterial vessels of the rat and rabbit J Cardiovasc Pharmacol. 1989;13 Suppl 5:S85-8; discussion S102.
- Tlmaque S, DOrlans-Juste P. Presence of a phosphoramidon-sensitive endothelin-converting enzyme which converts big-endothelin-1, but not big-endothelin-3, in the rat vas deferens Naunyn Schmiedebergs Arch Pharmacol. 1991 Oct;344(4):505-7.









