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GRP78 (human, recombinant)

Original price was: $149.00.Current price is: $37.25.

SKU: PW14836849549 Category:

Description

GRP78 (human, recombinant)

Catalog number: B2017311
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 50 g
Molecular Weight or Concentration: 74.6 kDa
Supplied as: Solution
Applications: a molecular tool for various biochemical applications
Storage: 80C
Keywords: BiP, Glucose-Regulated Protein 78, HspA5
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity>18 M-cm) and are filtered through 0.22 um.

References

  • Thakur G, Sathe G, Kundu I, Biswas B, Gautam P, Alkahtani S, Idicula-Thomas S, Sirdeshmukh R, Kishore U, Madan T. Membrane Interactome of a Recombinant Fragment of Human Surfactant Protein D Reveals GRP78 as a Novel Binding Partner in PC3, a Metastatic Prostate Cancer Cell Line Front Immunol. 2021 Jan 19;11:600660.
  • Lam TYW, Nguyen N, Peh HY, Shanmugasundaram M, Chandna R, Tee JH, Ong CB, Hossain MZ, Venugopal S, Zhang T, Xu S, Qiu T, Kong WT, Chakarov S, Srivastava S, Liao W, Kim JS, Teh M, Ginhoux F, Fred Wong WS, Ge R. ISM1 protects lung homeostasis via cell-surface GRP78-mediated alveolar macrophage apoptosis Proc Natl Acad Sci U S A. 2022 Jan 25;119(4):e2019161119.
  • Wei J, Chen X, Li Y, Li R, Bao K, Liao L, Xie Y, Yang T, Zhu J, Mao F, Ni S, Jia R, Xu X, Li J. Cucurbitacin B-induced G2/M cell cycle arrest of conjunctival melanoma cells mediated by GRP78-FOXM1-KIF20A pathway Acta Pharm Sin B. 2022 Oct;12(10):3861-3876.
  • Fabarius A, Samra V, Drews O, Mrz H, Bierbaum M, Darwich A, Weiss C, Brendel S, Kleiner H, Seifarth W, Greffrath W, Hofmann WK, Schmitt CA, Popp HD. Evidence for Recombinant GRP78, CALR, PDIA3 and GPI as Mediators of Genetic Instability in Human CD34+ Cells Cancers (Basel). 2022 Jun 11;14(12):2883.
  • Marn-Briggiler CI, Gonzlez-Echeverra MF, Munuce MJ, Ghersevich S, Caille AM, Hellman U, Corrigall VM, Vazquez-Levin MH. Glucose-regulated protein 78 (Grp78/BiP) is secreted by human oviduct epithelial cells and the recombinant protein modulates sperm-zona pellucida binding Fertil Steril. 2010 Mar 15;93(5):1574-84.
  • Tee JH, Vijayakumar U, Shanmugasundaram M, Lam TYW, Liao W, Yang Y, Wong WSF, Ge R. Isthmin-1 attenuates allergic Asthma by stimulating adiponectin expression and alveolar macrophage efferocytosis in mice Respir Res. 2023 Nov 6;24(1):269.
  • Ghaderi S, Ahmadian S, Soheili ZS, Ahmadieh H, Samiei S, Kheitan S, Pirmardan ER. AAV delivery of GRP78/BiP promotes adaptation of human RPE cell to ER stress J Cell Biochem. 2018 Feb;119(2):1355-1367.
  • Yao VJ, DAngelo S, Butler KS, Theron C, Smith TL, Marchi S, Gelovani JG, Sidman RL, Dobroff AS, Brinker CJ, Bradbury ARM, Arap W, Pasqualini R. Ligand-targeted theranostic nanomedicines against cancer J Control Release. 2016 Oct 28;240:267-286.
  • Qi AL, Wu Y, Dong N, Chai YF, Zhu XM, Yao YM. Recombinant human ulinastatin improves immune dysfunction of dendritic cells in septic mice by inhibiting endoplasmic reticulum stress-related apoptosis Int Immunopharmacol. 2020 Aug;85:106643.