Description
Human ACAT2 Protein
| Catalog number: | B2011062 |
| Lot number: | Batch Dependent |
| Expiration Date: | Batch dependent |
| Amount: | 100 ug |
| Molecular Weight or Concentration: | na |
| Supplied as: | Solution |
| Applications: | molecular tool for various chemical, biochemical and immunological applications |
| Storage: | -20C |
| Keywords: | Acetyl-CoA acetyltransferase protein, cytosolic, ACAT-2 protein, ACTL protein, ACAT2, ACAT 2 protein, ACAT-2, ACAT 2 |
| Grade: | Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity>18 M-cm) and are filtered through 0.22 um. |
References
- Wang YJ, Bian Y, Luo J, Lu M, Xiong Y, Guo SY, Yin HY, Lin X, Li Q, Chang CCY, Chang TY, Li BL, Song BL. Cholesterol and fatty acids regulate cysteine ubiquitylation of ACAT2 through competitive oxidation Nat Cell Biol. 2017 Jul;19(7):808-819.
- Goudarzi A. The recent insights into the function of ACAT1: A possible anti-cancer therapeutic target Life Sci. 2019 Sep 1;232:116592.
- Guo D, Zhang X, Li Q, Qian L, Xu J, Lu M, Hu X, Zhu M, Chang CC, Song B, Chang T, Xiong Y, Li B. The ACAT2 expression of human leukocytes is responsible for the excretion of lipoproteins containing cholesteryl/steryl esters Acta Biochim Biophys Sin (Shanghai). 2016 Nov;48(11):990-997.
- Yao XM, Wang CH, Song BL, Yang XY, Wang ZZ, Qi W, Lin ZX, Chang CC, Chang TY, Li BL. Two human ACAT2 mRNA variants produced by alternative splicing and coding for novel isoenzymes Acta Biochim Biophys Sin (Shanghai). 2005 Dec;37(12):797-806.
- Parini P, Jiang ZY, Einarsson C, Eggertsen G, Zhang SD, Rudel LL, Han TQ, Eriksson M. ACAT2 and human hepatic cholesterol metabolism: identification of important gender-related differences in normolipidemic, non-obese Chinese patients Atherosclerosis. 2009 Nov;207(1):266-71.
- Guo D, Lu M, Hu X, Xu J, Hu G, Zhu M, Zhang X, Li Q, Chang CC, Chang T, Song B, Xiong Y, Li B. Low-level expression of human ACAT2 gene in monocytic cells is regulated by the C/EBP transcription factors Acta Biochim Biophys Sin (Shanghai). 2016 Nov;48(11):980-989.
- Bastrup J, Hansen KH, Poulsen TBG, Kastaniegaard K, Asuni AA, Christensen S, Belling D, Helboe L, Stensballe A, Volbracht C. Anti-A Antibody Aducanumab Regulates the Proteome of Senile Plaques and Closely Surrounding Tissue in a Transgenic Mouse Model of Alzheimers Disease J Alzheimers Dis. 2021;79(1):249-265.
- Parini P, Davis M, Lada AT, Erickson SK, Wright TL, Gustafsson U, Sahlin S, Einarsson C, Eriksson M, Angelin B, Tomoda H, Omura S, Willingham MC, Rudel LL. ACAT2 is localized to hepatocytes and is the major cholesterol-esterifying enzyme in human liver Circulation. 2004 Oct 5;110(14):2017-23.
- Cheng L, Cao H, Xu J, Xu M, He W, Zhang W, Dong L, Chen D. Circ_RPL23A acts as a miR-1233 sponge to suppress the progression of clear cell renal cell carcinoma by promoting ACAT2 J Bioenerg Biomembr. 2021 Aug;53(4):415-428.
