Description
Human Alpha-1-Antitrypsin Deficient Heparin Plasma
| Catalog number: | B2014886 |
| Lot number: | Batch Dependent |
| Expiration Date: | Batch dependent |
| Amount: | 1 mL |
| Molecular Weight or Concentration: | N/A |
| Supplied as: | Lyophilized Plasma |
| Applications: | molecular tool for various biochemical applications |
| Storage: | -20 C |
| Keywords: | alpha-1-Antitripsin, A1AT, Alpha-1 Protease Inhibitor, Alpha-1-Antiproteinase, Serpin A1, SPAAT, SERPINA1, AAT |
| Grade: | Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity>18 M-cm) and are filtered through 0.22 um. |
References
- Beresford CH. Antithrombin III deficiency Blood Rev. 1988 Dec;2(4):239-50.
- Heeb MJ, Griffin JH. Physiologic inhibition of human activated protein C by alpha 1-antitrypsin J Biol Chem. 1988 Aug 25;263(24):11613-6.
- van der Meer FJ, van Tilburg NH, van Wijngaarden A, van der Linden IK, Brit E, Bertina RM. A second plasma inhibitor of activated protein C: alpha 1-antitrypsin Thromb Haemost. 1989 Sep 29;62(2):756-62.
- Belorgey D, Hgglf P, Karlsson-Li S, Lomas DA. Protein misfolding and the serpinopathies Prion. 2007 Jan-Mar;1(1):15-20.
- Lane DA, Olds RR, Thein SL. Antithrombin and its deficiency states Blood Coagul Fibrinolysis. 1992 Jun;3(3):315-41.
- Gooptu B, Lomas DA. Conformational pathology of the serpins: themes, variations, and therapeutic strategies Annu Rev Biochem. 2009;78:147-76.
- Borsodi AD, Bradshaw RA. Isolation of antithrombin III from normal and alpha1-antitrypsin-deficient human plasma Thromb Haemost. 1977 Aug 31;38(2):475-85.
- Kounnas MZ, Church FC, Argraves WS, Strickland DK. Cellular internalization and degradation of antithrombin III-thrombin, heparin cofactor II-thrombin, and alpha 1-antitrypsin-trypsin complexes is mediated by the low density lipoprotein receptor-related protein J Biol Chem. 1996 Mar 15;271(11):6523-9.
- Bauer KA, Goodman TL, Kass BL, Rosenberg RD. Elevated factor Xa activity in the blood of asymptomatic patients with congenital antithrombin deficiency J Clin Invest. 1985 Aug;76(2):826-36.
