Description
Human CARD18 Protein
| Catalog number: | B2011695 |
| Lot number: | Batch Dependent |
| Expiration Date: | Batch dependent |
| Amount: | 50 g |
| Molecular Weight or Concentration: | 500 g/mL |
| Supplied as: | Solution |
| Applications: | molecular tool for various biochemical applications |
| Storage: | -20 C |
| Keywords: | pseudo-ICE protein, CARD-18, Caspase recruitment domain-containing protein 18 protein, ICEBERG protein, CARD18, CARD 18, CARD-18 protein, UNQ5804 protein, CARD 18 protein |
| Grade: | Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity>18 M-cm) and are filtered through 0.22 um. |
References
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- Qin H, Jin J, Fischer H, Mildner M, Gschwandtner M, Mlitz V, Eckhart L, Tschachler E. The caspase-1 inhibitor CARD18 is specifically expressed during late differentiation of keratinocytes and its expression is lost in lichen planus J Dermatol Sci. 2017 Aug;87(2):176-182.
- Lu A, Li Y, Schmidt FI, Yin Q, Chen S, Fu TM, Tong AB, Ploegh HL, Mao Y, Wu H. Molecular basis of caspase-1 polymerization and its inhibition by a new capping mechanism Nat Struct Mol Biol. 2016 May;23(5):416-25.
- Gbls A, Danis J, Vas K, Bata-Csrg Z, Kemny L, Szll M. Keratinocytes express functional CARD18, a negative regulator of inflammasome activation, and its altered expression in psoriasis may contribute to disease pathogenesis Mol Immunol. 2016 May;73:10-8.
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- Tan C, Liu S, Xiang Z. [The expression of CARD18 in apoptin-transfected gastric cancer cells and gastric adenocarcinoma tissues] Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2013 Aug;29(8):858-61.
- Wright CM, Savarimuthu Francis SM, Tan ME, Martins MU, Winterford C, Davidson MR, Duhig EE, Clarke BE, Hayward NK, Yang IA, Bowman RV, Fong KM. MS4A1 dysregulation in asbestos-related lung squamous cell carcinoma is due to CD20 stromal lymphocyte expression PLoS One. 2012;7(4):e34943.
- Johansson , Eriksson N, Becker RC, Storey RF, Himmelmann A, Hagstrm E, Varenhorst C, Axelsson T, Barratt BJ, James SK, Katus HA, Steg PG, Syvnen AC, Wallentin L, Siegbahn A; PLATO Investigators. NLRC4 Inflammasome Is an Important Regulator of Interleukin-18 Levels in Patients With Acute Coronary Syndromes: Genome-Wide Association Study in the PLATelet inhibition and patient Outcomes Trial (PLATO) Circ Cardiovasc Genet. 2015 Jun;8(3):498-506.
