Description
Human Glu-Plasminogen
| Catalog number: | B2013362 |
| Lot number: | Batch Dependent |
| Expiration Date: | Batch dependent |
| Amount: | 1 mg |
| Molecular Weight or Concentration: | 90 kDa |
| Supplied as: | Plasma |
| Applications: | molecular tool for various biochemical applications |
| Storage: | -20C |
| Keywords: | Human Glu-Plasminogen |
| Grade: | Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity>18 M-cm) and are filtered through 0.22 um. |
References
- Keragala CB, Medcalf RL. Plasminogen: an enigmatic zymogen Blood. 2021 May 27;137(21):2881-2889.
- Castellino FJ, Powell JR. Human plasminogen Methods Enzymol. 1981;80 Pt C:365-78.
- Chen LY, Mehta JL. Lys- and glu-plasminogen potentiate the inhibitory effect of recombinant tissue plasminogen activator on human platelet aggregation Thromb Res. 1994 Jun 15;74(6):555-63.
- Celkan T. Plasminogen deficiency J Thromb Thrombolysis. 2017 Jan;43(1):132-138.
- Tran-Thang C, Kruithof EK, Atkinson J, Bachmann F. High-affinity binding sites for human Glu-plasminogen unveiled by limited plasmic degradation of human fibrin Eur J Biochem. 1986 Nov 3;160(3):599-604.
- Fredenburgh JC, Nesheim ME. Lys-plasminogen is a significant intermediate in the activation of Glu-plasminogen during fibrinolysis in vitro J Biol Chem. 1992 Dec 25;267(36):26150-6.
- Romagnuolo R, DeMarco K, Scipione CA, Boffa MB, Koschinsky ML. Apolipoprotein(a) inhibits the conversion of Glu-plasminogen to Lys-plasminogen on the surface of vascular endothelial and smooth muscle cells Thromb Res. 2018 Sep;169:1-7.
- Miles LA, Castellino FJ, Gong Y. Critical role for conversion of glu-plasminogen to Lys-plasminogen for optimal stimulation of plasminogen activation on cell surfaces Trends Cardiovasc Med. 2003 Jan;13(1):21-30.
- Gong Y, Kim SO, Felez J, Grella DK, Castellino FJ, Miles LA. Conversion of Glu-plasminogen to Lys-plasminogen is necessary for optimal stimulation of plasminogen activation on the endothelial cell surface J Biol Chem. 2001 Jun 1;276(22):19078-83.
