Description
Human GPX1
| Catalog number: | B2016771 |
| Lot number: | Batch Dependent |
| Expiration Date: | Batch dependent |
| Amount: | 50 g |
| Molecular Weight or Concentration: | N/A |
| Supplied as: | Solution |
| Applications: | a molecular tool for various biochemical applications |
| Storage: | 20C |
| Keywords: | Glutathione Peroxidase 1, GPXD, GSHPX1 |
| Grade: | Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity>18 M-cm) and are filtered through 0.22 um. |
References
- Cheff DM, Cheng Q, Guo H, Travers J, Klumpp-Thomas C, Shen M, Arnr ESJ, Hall MD. Development of an assay pipeline for the discovery of novel small molecule inhibitors of human glutathione peroxidases GPX1 and GPX4 Redox Biol. 2023 Jul;63:102719.
- Schwarz M, Lser A, Cheng Q, Wichmann-Costaganna M, Schdel P, Werz O, Arnr ES, Kipp AP. Side-by-side comparison of recombinant human glutathione peroxidases identifies overlapping substrate specificities for soluble hydroperoxides Redox Biol. 2023 Feb;59:102593.
- Cheng Q, Roveri A, Cozza G, Bordin L, Rohn I, Schwerdtle T, Kipp A, Ursini F, Maiorino M, Miotto G, Arnr ESJ. Production and purification of homogenous recombinant human selenoproteins reveals a unique codon skipping event in E. coli and GPX4-specific affinity to bromosulfophthalein Redox Biol. 2021 Oct;46:102070.
- Han X, Fan Z, Yu Y, Liu S, Hao Y, Huo R, Wei J. Expression and characterization of recombinant human phospholipid hydroperoxide glutathione peroxidase IUBMB Life. 2013 Nov;65(11):951-6.
- Mukai T, Sevostyanova A, Suzuki T, Fu X, Sll D. A Facile Method for Producing Selenocysteine-Containing Proteins Angew Chem Int Ed Engl. 2018 Jun 11;57(24):7215-7219.
- Fradejas-Villar N, Bohleber S, Zhao W, Reuter U, Kotter A, Helm M, Knoll R, McFarland R, Taylor RW, Mo Y, Miyauchi K, Sakaguchi Y, Suzuki T, Schweizer U. The Effect of tRNA([Ser]Sec) Isopentenylation on Selenoprotein Expression Int J Mol Sci. 2021 Oct 23;22(21):11454.
- Guo X, Song J, Yu Y, Wei J. Can recombinant human glutathione peroxidase 1 with high activity be efficiently produced in Escherichia coli ? Antioxid Redox Signal. 2014 Mar 20;20(9):1524-30.
- Faucher K, Rabinovitch-Chable H, Cook-Moreau J, Barrire G, Sturtz F, Rigaud M. Overexpression of human GPX1 modifies Bax to Bcl-2 apoptotic ratio in human endothelial cells Mol Cell Biochem. 2005 Sep;277(1-2):81-7.
- Cheng AWM, Bolognesi M, Kraus VB. DIO2 modifies inflammatory responses in chondrocytes Osteoarthritis Cartilage. 2012 May;20(5):440-445.
