Description
Myristolated PKCz Pseudosubstrate ZIP Scrambled
| Catalog number: | B2011210 |
| Lot number: | Batch Dependent |
| Expiration Date: | Batch dependent |
| Amount: | 1 mg |
| Molecular Weight or Concentration: | 1928.5 |
| Supplied as: | Lyophilized |
| Applications: | molecular tool for various biochemical applications |
| Storage: | -20 C |
| Keywords: | Myristolated PKC Zeta Pseudosubstrate ZIP Scrambled |
| Grade: | Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity>18 M-cm) and are filtered through 0.22 um. |
References
- Lim S, Choi JW, Kim HS, Kim YH, Yea K, Heo K, Kim JH, Kim SH, Song M, Kim JI, Ryu SH, Suh PG. A myristoylated pseudosubstrate peptide of PKC-zeta induces degranulation in HMC-1 cells independently of PKC-zeta activity Life Sci. 2008 Mar 26;82(13-14):733-40.
- Lee-Rivera I, Lpez E, Alvarez-Arce A, Lpez-Colom AM. The PKC- pseudosubstrate peptide induces glutamate release from retinal pigment epithelium cells through kinase- independent activation of Best1 Life Sci. 2021 Jan 15;265:118860.
- Eichholtz T, de Bont DB, de Widt J, Liskamp RM, Ploegh HL. A myristoylated pseudosubstrate peptide, a novel protein kinase C inhibitor J Biol Chem. 1993 Jan 25;268(3):1982-6.
- Verhoeven AJ, Leusen JH, Kessels GC, Hilarius PM, de Bont DB, Liskamp RM. Inhibition of neutrophil NADPH oxidase assembly by a myristoylated pseudosubstrate of protein kinase C J Biol Chem. 1993 Sep 5;268(25):18593-8.
- Cao YJ, Li JY, Wang PX, Lin ZR, Yu WJ, Zhang JG, Lu J, Liu PQ. PKC- Aggravates Doxorubicin-Induced Cardiotoxicity by Inhibiting Wnt/-Catenin Signaling Front Pharmacol. 2022 Feb 14;13:798436.
- Harris TE, Persaud SJ, Saermark T, Jones PM. A myristoylated pseudosubstrate peptide inhibitor of protein kinase C: effects on glucose- and carbachol-induced insulin secretion Mol Cell Endocrinol. 1996 Aug 9;121(2):133-41.
- Harishchandran A, Nagaraj R. Interaction of a pseudosubstrate peptide of protein kinase C and its myristoylated form with lipid vesicles: only the myristoylated form translocates into the lipid bilayer Biochim Biophys Acta. 2005 Jul 30;1713(2):73-82.
- Bergman PJ, Gravitt KR, Ward NE, Beltran P, Gupta KP, OBrian CA. Potent induction of human colon cancer cell uptake of chemotherapeutic drugs by N-myristoylated protein kinase C-alpha (PKC-alpha) pseudosubstrate peptides through a P-glycoprotein-independent mechanism Invest New Drugs. 1997;15(4):311-8.
- Gupta KP, Ward NE, Gravitt KR, Bergman PJ, OBrian CA. Partial reversal of multidrug resistance in human breast cancer cells by an N-myristoylated protein kinase C-alpha pseudosubstrate peptide J Biol Chem. 1996 Jan 26;271(4):2102-11.
