Description
PACAP27 (Human, 1-27 Amide)
| Catalog number: | MDP0616 |
| CAS Number: | 131602-53-4 |
| Sequence: | His-Ser-Asp-Gly-Ile-Phe-Thr-Asp-Ser-Tyr-Ser-Arg-Tyr-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-NH2 |
| Amount: | 500 ug |
| Molecular Weight: | 3147.6 g/mol |
| Supplied as: | Powder |
| Applications: | molecular tool for various biochemical applications |
| Storage: | -20 C |
| WARNING: | For in vitro Research Use Only. NOT for use on humans or animals. |
| Grade: | Biotechnology grade. All products are highly pure. |
References
- Ghanizada H, Al-Karagholi MA, Arngrim N, Olesen J, Ashina M. PACAP27 induces migraine-like attacks in migraine patients Cephalalgia. 2020 Jan;40(1):57-67.
- Velasco ER, Florido A, Flores , Senabre E, Gomez-Gomez A, Torres A, Roca A, Norrholm S, Newman EL, Das P, Ross RA, Lori A, Pozo OJ, Ressler KJ, Garcia-Esteve LL, Jovanovic T, Andero R. PACAP-PAC1R modulates fear extinction via the ventromedial hypothalamus Nat Commun. 2022 Jul 28;13(1):4374.
- Yan BM, Gibson Depoy EM, Ahmad A, Nahas SJ. Biomarkers in Migraine Neurol India. 2021 Mar-Apr;69(Supplement):S17-S24.
- Ashina H, Guo S, Vollesen ALH, Ashina M. PACAP38 in human models of primary headaches J Headache Pain. 2017 Nov 23;18(1):110.
- Liu J, Wang G, Dan Y, Liu X. CGRP and PACAP-38 play an important role in diagnosing pediatric migraine J Headache Pain. 2022 Jun 13;23(1):68.
- Rozzi SJ, Borelli G, Ryan K, Steiner JP, Reglodi D, Mocchetti I, Avdoshina V. PACAP27 is protective against tat-induced neurotoxicity J Mol Neurosci. 2014 Nov;54(3):485-93.
- Moody TW, Jensen RT. Pituitary adenylate cyclase-activating polypeptide/vasoactive intestinal peptide (Part 2): biology and clinical importance in central nervous system and inflammatory disorders Curr Opin Endocrinol Diabetes Obes. 2021 Apr 1;28(2):206-213.
- Patko E, Szabo E, Toth D, Tornoczky T, Bosnyak I, Vaczy A, Atlasz T, Reglodi D. Distribution of PACAP and PAC1 Receptor in the Human Eye J Mol Neurosci. 2022 Nov;72(11):2176-2187.
- Tassorelli C, De Icco R. Getting closer to a cure for migraine Nat Rev Neurol. 2019 Feb;15(2):64-65.
