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Phospho-SLP-76 (Tyr128) Rabbit Antibody APC Conjugate

Original price was: $145.00.Current price is: $36.25.

SKU: PW14836860258 Category:

Description

Phospho-SLP-76 (Tyr128) Rabbit Antibody APC Conjugate

Catalog number: B2018366
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 10 Tests
Molecular Weight or Concentration: N/A
Supplied as: Solution
Applications: a molecular tool for various biochemical applications
Storage: 2-8 C
Keywords: Apoptosis signal-regulating kinase 1, Mitogen-activated protein kinase kinase kinase 5, MAPK/ERK kinase kinase 5, MAP3K5, MAPKKK5, MEKK5
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity>18 M-cm) and are filtered through 0.22 um.

References

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  • Lewis JB, Scangarello FA, Murphy JM, Eidell KP, Sodipo MO, Ophir MJ, Sargeant R, Seminario MC, Bunnell SC. ADAP is an upstream regulator that precedes SLP-76 at sites of TCR engagement and stabilizes signaling microclusters J Cell Sci. 2018 Nov 8;131(21):jcs215517.
  • Yablonski D. Bridging the Gap: Modulatory Roles of the Grb2-Family Adaptor, Gads, in Cellular and Allergic Immune Responses Front Immunol. 2019 Jul 25;10:1704.
  • Yen A, Varvayanis S, Smith JL, Lamkin TJ. Retinoic acid induces expression of SLP-76: expression with c-FMS enhances ERK activation and retinoic acid-induced differentiation/G0 arrest of HL-60 cells Eur J Cell Biol. 2006 Feb;85(2):117-32.
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  • Breuning J, Philip B, Brown MH. Addition of the C-terminus of CD6 to a chimeric antigen receptor enhances cytotoxicity and does not compromise expression Immunology. 2019 Feb;156(2):130-135.
  • Sylvester M, Kliche S, Lange S, Geithner S, Klemm C, Schlosser A, Grossmann A, Stelzl U, Schraven B, Krause E, Freund C. Adhesion and degranulation promoting adapter protein (ADAP) is a central hub for phosphotyrosine-mediated interactions in T cells PLoS One. 2010 Jul 22;5(7):e11708.
  • Petti F, Thelemann A, Kahler J, McCormack S, Castaldo L, Hunt T, Nuwaysir L, Zeiske L, Haack H, Sullivan L, Garton A, Haley JD. Temporal quantitation of mutant Kit tyrosine kinase signaling attenuated by a novel thiophene kinase inhibitor OSI-930 Mol Cancer Ther. 2005 Aug;4(8):1186-97.