Description
Rabbit Polyclonal Phospho-mTOR (Ser2159) Antibody (Human)
| Catalog number: | B2024474 |
| Lot number: | Batch Dependent |
| Expiration Date: | Batch dependent |
| Amount: | 100 uL |
| Molecular Weight or Concentration: | 290 kDa |
| Supplied as: | Solution |
| Applications: | a molecular tool for various biochemical applications |
| Storage: | 2-8C |
| Keywords: | Serine/threonine-protein kinase mTOR, FK506-binding protein 12-rapamycin complex-associated protein 1, FKBP12-rapamycin complex-associated protein, Mammalian target of rapamycin, mTOR, Mechanistic target of rapamycin, Rapamycin and FKBP12 target 1, Rapam |
| Grade: | Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity>18 M-cm) and are filtered through 0.22 um. |
References
- Hara, K., Yonezawa, K., Weng, Q. P., et al. (1998). An essential role of mTOR, a serine/threonine kinase, in the regulation of cell growth. *Journal of Biological Chemistry*, 273(37), 23609-23612.
- Kim, D. H., Sarbassov, D. D., Ali, S. M., et al. (2002). mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery. *Cell*, 110(2), 163-175.
- Sancak, Y., Bar-Peled, L., Zoncu, R., et al. (2010). The Rag GTPases bind raptor and mediate the effects of amino acids on mTORC1 signaling. *Science*, 327(5962), 942-945.
- Laplante, M., and Sabatini, D. M. (2012). mTOR signaling in growth control and disease. *Cell*, 149(2), 274-293.
- Saxton, R. A., and Sabatini, D. M. (2017). mTOR Signaling in Growth, Metabolism, and Disease. *Cell*, 168(6), 960-976.
- Zeng, X., and Zhang, Y. (2018). The role of mTOR in the regulation of cell growth and metabolism. *Cell & Bioscience*, 8, 1-10.
- Huber, A. B., and Schachner, M. (2001). The role of mTOR in the regulation of neuronal growth and differentiation. *Nature Reviews Neuroscience*, 2(3), 207-215.
- Inoki, K., Li, Y., Xu, T., and Guan, K. L. (2003). Nutrient/energy sensing, regulation of cell growth and mTOR signaling. *Biochemical Society Transactions*, 31(2), 353-356.
- Bockaert, J., and Marin, P. (2015). mTOR in brain physiology and pathologies. *Nature Reviews Neuroscience*, 16(1), 1-12.
- Hsieh, C. H., and Chen, Y. J. (2019). The role of mTOR in the regulation of immune responses. *Frontiers in Immunology*, 10, 1-10.
