Description
Sphingomyelin Synthase 2 (aa 1-79) Human Recombinant
| Catalog number: | B2017564 |
| Lot number: | Batch Dependent |
| Expiration Date: | Batch dependent |
| Amount: | 50 g |
| Molecular Weight or Concentration: | 35.7 kDa |
| Supplied as: | POWDER |
| Applications: | a molecular tool for various biochemical applications |
| Storage: | -80C |
| Keywords: | Phosphatidylcholine:ceramide Cholinephosphotransferase 2, SMS2 |
| Grade: | Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity>18 M-cm) and are filtered through 0.22 um. |
References
- Lou B, Liu Q, Hou J, Kabir I, Liu P, Ding T, Dong J, Mo M, Ye D, Chen Y, Bui HH, Roth K, Cao Y, Jiang XC. 2-Hydroxy-oleic acid does not activate sphingomyelin synthase activity J Biol Chem. 2018 Nov 23;293(47):18328-18336.
- Wang X, Dong J, Zhao Y, Li Y, Wu M. Adenovirus-mediated sphingomyelin synthase 2 increases atherosclerotic lesions in ApoE KO mice Lipids Health Dis. 2011 Jan 17;10:7.
- Li Y, Dong J, Ding T, Kuo MS, Cao G, Jiang XC, Li Z. Sphingomyelin synthase 2 activity and liver steatosis: an effect of ceramide-mediated peroxisome proliferator-activated receptor 2 suppression Arterioscler Thromb Vasc Biol. 2013 Jul;33(7):1513-20.
- Zhao YR, Dong JB, Li Y, Wu MP. Sphingomyelin synthase 2 over-expression induces expression of aortic inflammatory biomarkers and decreases circulating EPCs in ApoE KO mice Life Sci. 2012 Jun 6;90(21-22):867-73.
- Albi E, La Porta CA, Cataldi S, Magni MV. Nuclear sphingomyelin-synthase and protein kinase C delta in melanoma cells Arch Biochem Biophys. 2005 Jun 15;438(2):156-61.
- Dong J, Liu J, Lou B, Li Z, Ye X, Wu M, Jiang XC. Adenovirus-mediated overexpression of sphingomyelin synthases 1 and 2 increases the atherogenic potential in mice J Lipid Res. 2006 Jun;47(6):1307-14.
- Lee WK, Torchalski B, Kohistani N, Thvenod F. ABCB1 protects kidney proximal tubule cells against cadmium-induced apoptosis: roles of cadmium and ceramide transport Toxicol Sci. 2011 Jun;121(2):343-56.
- Luberto C, Hannun YA. Sphingomyelin synthase, a potential regulator of intracellular levels of ceramide and diacylglycerol during SV40 transformation. Does sphingomyelin synthase account for the putative phosphatidylcholine-specific phospholipase C? J Biol Chem. 1998 Jun 5;273(23):14550-9.
- Chandran S, Machamer CE. Inactivation of ceramide transfer protein during pro-apoptotic stress by Golgi disassembly and caspase cleavage Biochem J. 2012 Mar 1;442(2):391-401.
