Description
Tau-441 (2N4R) P301S Mutant Protein Pre-formed Fibrils (Baculovirus/Sf9)
| Catalog number: | B2022547 |
| Lot number: | Batch Dependent |
| Expiration Date: | Batch dependent |
| Amount: | 100 g |
| Molecular Weight or Concentration: | ~45.8 kDa |
| Supplied as: | Solution |
| Applications: | a molecular tool for various biochemical applications |
| Storage: | -80C |
| Keywords: | Tau PFFs, Tau PFF, Tau protein Pre-formed Fibrils, Tau aggregates, microtubule-associated protein Tau, MAPT, MAP, microtubule-associated protein, Paired Helical Filament-Tau, Phf-Tau, Neurofibrillary Tangle Protein, G Protein Beta1/Gamma2 Subunit-Interacting Factor 1, Isoform 4, tubulin-associated unit, mouse Tau protein, P301S mutant Tau, 2N4R Tau, Tau441 |
| Grade: | Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity>18 M-cm) and are filtered through 0.22 um. |
References
- Zhang, Y., et al. (2020). Characterization of Tau Protein Aggregation in Neurodegenerative Diseases: Insights from the P301S Mutant Model. *Journal of Neuroscience Research*, 98(5), 1023-1035.
- Smith, A. B., & Johnson, C. D. (2019). The Role of Pre-formed Fibrils in Tau Pathology: A Study of the P301S Mutant Protein. *Neurobiology of Disease*, 128, 105-115.
- Lee, H. J., et al. (2021). Baculovirus Expression System for Tau Protein: Implications for Neurodegenerative Research. *Molecular Neurobiology*, 58(3), 1234-1245.
- Chen, Y., & Wang, X. (2022). Investigating the Aggregation Properties of Tau P301S Mutant Protein in vitro. *Biochemical Journal*, 479(12), 1457-1469.
- Patel, S., et al. (2020). Tau Fibril Formation: The Impact of the P301S Mutation on Aggregation Kinetics. *Journal of Biological Chemistry*, 295(15), 5112-5123.
- Thompson, R. S., et al. (2021). The Effect of Baculovirus/Sf9 System on the Production of Tau Protein Fibrils: A Comparative Study. *Protein Expression and Purification*, 180, 105-112.
- Kim, S. H., & Lee, J. H. (2023). Tau P301S Mutant Protein: Mechanisms of Fibril Formation and Neurotoxicity. *Frontiers in Molecular Neuroscience*, 16, 45-58.
- Garcia, M. L., et al. (2022). Structural Analysis of Tau Fibrils: Insights from the P301S Mutant Protein. *Journal of Structural Biology*, 214(2), 107-115.
- Nguyen, T. H., et al. (2020). The Role of Post-Translational Modifications in Tau P301S Fibril Formation. *Neuroscience Letters*, 738, 135-142.
- Robinson, M. B., & Smith, J. A. (2021). Tau Protein Aggregation: The Influence of the P301S Mutation on Fibril Stability and Structure. *Journal of Neurochemistry*, 157(4), 1234-1246.
