Description
Triiodothyronine BSA Conjugate
| Catalog number: | B2012115 |
| Lot number: | Batch Dependent |
| Expiration date: | Batch Dependent |
| Amount: | 5 mg |
| Molecular Weight: | N/A |
| Supplied as: | Liquid |
| Storage: | 20C |
| Keywords: | T3, T3-BSA conjugate |
| Grade: | Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity>18 Mcm) and are filtered through 0.22 m. |
Triiodothyronine BSA Conjugate is a chemically modified form of the thyroid hormone triiodothyronine (T3), covalently linked to bovine serum albumin (BSA) for enhanced stability and assay compatibility. This conjugate is widely used in immunoassay development, receptor binding studies, and endocrine research. By tethering T3 to BSA, the molecule becomes suitable for coating ELISA plates, generating antibodies, and studying hormone-receptor interactions without rapid degradation or diffusion.
T3 is a critical regulator of metabolism, growth, and development. Its conjugation to BSA allows for controlled presentation in biochemical assays, enabling researchers to investigate thyroid hormone uptake, transport, and cellular response mechanisms. The conjugate is especially useful in competitive immunoassays, where it serves as a labeled antigen to quantify free or total T3 levels in biological samples.
This reagent is supplied in liquid format at 5 mg and is compatible with manual and automated platforms. It is formulated in ultrapure water and filtered through 0.22 m membranes to ensure purity and reproducibility. Applications span endocrinology, toxicology, and pharmacology, including studies on stress response, thyroid dysfunction, and hormone metabolism.
Key benefits:
- Triiodothyronine conjugated to BSA for enhanced assay stability
- Supports ELISA, immunoassay development, and receptor binding studies
- Widely used in thyroid hormone metabolism and endocrine research
- Biotechnology grade; filtered through 0.22 m membranes
- Supplied at 5 mg; store at 20C to maintain activity
Products are for in vitro research use only (RUO).
References
- Wani TA et al. Flow immunosensor detection of T3 and thyroxine. Drug Dev Technol. 2016 Nov;14(9):535542.
- Santini F et al. Hepatic iodothyronine deiodinase characterization. Endocrinology. 1992 Aug;131(2):830834.
- Santini F et al. Rat placental vs hepatic deiodinase. Endocrinology. 1992 Apr;130(4):23252332.
- Farmer C et al. Hormonal changes under acute stress. Domest Anim Endocrinol. 1991 Oct;8(4):527536.
- Rutgers M et al. TA3 metabolism in rat liver. Endocrinology. 1989 Jul;125(1):433443.
- Doctor R et al. Inhibition of thyroid hormone uptake. Endocrinology. 1988 Sep;123(3):15201525.
- Derkach KV et al. Immunization with BSA-conjugated peptides affects thyroid function. Tsitologiia. 2014;56(11):850857.
- Everts ME et al. Thyroxine uptake in pituitary cells. Endocrinology. 1994 Jun;134(6):24902497.
- Kumari GL et al. Influence of iodothyronine conjugates on thyroid hormone ELISA. J Immunoassay Immunochem. 2014;35(2):139156.
- Derkach KV et al. Thyroid status in rats immunized with melanocortin receptor peptides. Zh Evol Biokhim Fiziol. 2015 JulAug;51(4):243250.
